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HIV High-Impact Prevention


 Getting to Zero

For decades, the numbers of newly infected persons have remained stagnant. All our efforts at HIV prevention and education have not moved the needle. But in recent years, new approaches have started to make a difference. 

Two studiesHPTN-052 and the PARTNER study have shown that an HIV-positive person in a relationship with an HIV-negative partner has virtually no chance of transmitting HIV, so long as they are on medication and have an undetectable viral load. In the simplest of terms, U=U; Undetectable equals Untransmittable. 

The big source of new infections are from persons who don't know they're positiveeither because they never tested for HIV or they became infected after their last negative test. For persons with a greater risk of becoming positive, studies have shown that a particular medication used for HIV treatmentTruvadawill also keep an HIV-negative person negative, by taking a pill a day. Participants in the IPrEX study reduced their risk by about half. For the persons who took the drug daily, their risk of becoming HIV-positive was reduced by 99%.

Together, these medical interventions can stop the spread of HIV. 

TasP (Treatment as Prevention)

Whether you're newly diagnosed, are new to the area, or you've been out of care, the CARE Clinic can help you become undetectable. Our benefits specialists can sign you up for health insurance and other programs that will help cover the costs of your medical visits, lab work, and medications. If there are other issues in your life that are getting in the way, our in-house housing specialists, psychiatrists, plus CARE's therapists, dentists, and food bank are there to help. If you need it, you'll be assigned a case management team to offer help, guidance, and education along they way. To schedule your intake appointment, call (562) 624-4999 or email

PrEP (Pre-Exposure Prophylaxis)

Whether We've learned that among some populations, the risk of acquiring HIV is enormous. For young Black gay or bi men, the chance that they'll test positive in their lifetime is one in two. For Latinx men who have sex with men, the risk is one in four. For young gay men in general, their lifetime risk is one in nine. For trans persons, the risk is even higher. Other high-risk individuals include those who exchange sex for money, food, drugs, or a place to stay and folks who have an HIV-positive partner. In addition to condoms and safer sex, PrEP is highly effective at preventing HIV infection for those who take the medication. In addition, PrEP patients at care are regularly checked for HIV and other STDs, and their labs are closely monitored. To learn more about PrEP, contact Paul Lovely, the CARE Center's PrEP and PEP navigator at (562) 624-4963 or email

PEP (Post-Exposure Prophylaxis)

For individuals who've had a high-risk exposure, PEP can keep the person from becoming infected. A high-risk exposure is considered to be a needlestick injury from a needle or other sharps used on a known HIV-positive person or unprotected sex with a known positive person. By starting on medications for HIV right away, and taking them for four weeks, an exposed individual can greatly reduce the chance of becoming infected. But time is of the essence! Medications need to be started in 48 to 72 hours of exposure, and the sooner, the better. Because the CARE Center's PEP program in integrated into the Emergency Department of Dignity Health St. Mary Medical Center, a patient can access PEP in the evening and on weekends—the times when exposure is most likely to occur. For this reason, the CARE Center has been designated a PEP Center of Excellence by Los Angeles County. If you need to access PEP, contact Paul Lovely, the CARE Center's PEP navigator at (562) 624-4963 or come to the St. Mary Medical Center Emergency Room after regular business hours.


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